RAF Typhoon jets have operated alongside French warplanes in a combined operation on an hidden munitions depot in Syrian territory operated by the IS group, per a report from the UK's MoD.
The facility, identified by reconnaissance, was assessed as housing weapons and explosive materials, the statement said, and was located in mountainous terrain just to the north of the ancient city of Palmyra in Syria's central region.
"Our fighter planes used precision-guided Paveway IV munitions to strike a number of approach shafts down to the facility... preliminary assessments are that the strike was effective," the ministry announced.
There was no indication of any civilian casualties in the attack late on Saturday and all the aircraft returned to base without incident, the ministry further stated.
The Typhoon fighters were supported by a Voyager aerial refuelling aircraft.
The Islamic State group - alternatively referred to as the so-called Islamic State - established jihadist rule over parts of Iraq and Syria until 2019.
"This operation underscores British leadership, and resolve to stand shoulder to shoulder with allied nations, to eradicate any re-emergence of the terrorist group and their harmful and extremist ideologies in the area," Britain's Defence Chief the minister stated.
UK warplanes have performed surveillance missions over Syrian airspace to "deter any attempted resurgence" of IS after its defeat at the Baghuz confrontation in 2019, the MoD reported.
"I want to thank the personnel of the UK armed forces involved in this operation for their skill and their valour," Healey said. "They were part of numerous British personnel deployed over the festive period. This action, to take out terrorist threats who threaten our safety, demonstrates how our armed forces are ready to step up, throughout the year, ensuring Britain's security within its borders and powerful internationally."
In December, the US military conducted what it called a "massive strike" targeting Islamic State objectives in the country, following an assault resulted in the deaths of two US servicemembers and a civilian linguist in Palmyra.
The United Nations says IS still maintains roughly 5-7 thousand combatants in Syria and Iraq.